Munir, Author at Juvena Therapeutics

Jyoti Ahlawat, PHD

Dr. Ahlawat joined Juvena Therapeutics as an Associate Scientist: Drug Discovery. She holds a Master’s degree in Biotechnology from the Indian Institute of Technology, Roorkee (IITR), and a Ph.D. in Chemistry from the University of Texas at El Paso (UTEP). She is a recipient of Academic and Research Excellence award from the College of Science (UTEP). Her dissertation research involved developing materials and testing them in-vitro to develop therapeutics against the gravest of human diseases such as Alzheimer’s (AD) and Parkinson’s disease (PD).

Dr. Ahlawat has published more than 18 articles and book chapters in international, peer-reviewed, reputed journals. She is a recipient of the title “Rising Star in Nanoscience and Nanotechnology” at the 10^th IEE International Conference on nanomaterials and applications (IEEE-NAP 2020). She has won Best presentation awards at the Equniox (2022), 26^th Annual BioEnvironmental Polymer Society (BEPS-2019), Graduate Expo (2018), and 8^th International conference on smart materials, structure, and systems (ISSS-2017). In addition, she has won various travel awards (2018-2020), four research awards (2019-2021), and graduate scholarships (2019-2020). She is an Editorial board member of the Journal Future Trends in Nanotechnology and is serving as a Guest Editor for Science Progress (SAGE Journal).

She has served as Vice president of Graduate Student Assembly (2018), and as President of BioChem graduate student chapter (2021). She recently received honorarium from Society for Science for serving as a Science Talent Search Evaluator in 2021. She received Certificate of Appreciation from the Graduate School for her contribution to Undergraduate Learning in 2021. She has served as science judge for the Sun Country Science & Engineering fair (2021), Regeneron International Science & Engineering fair (2021) and at 2^nd annual El Paso STEM expo competition (2019). She worked as an intern for eight months with a medical device company where she participated and led international projects which included renewal and registration of ophthalmic lenses in Mexico, Creating Instructions for Use (IFUs) and technical files, and Translation of IFUs into European languages.

Dr. Ahlawat serves as a peer-reviewer for journals such as Cell Biochemistry and Biophysics, Nanotechnology for Environmental Engineering, Environmental Science, Journal for Drug Delivery, and technology, and Phytotherapy. She delivered four invited scientific talks at International Conferences in 2021-2022.

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Horizon Ventures Techcracker conference spotlights Juvena Co-Founder, Hanadie Yousef, PhD as one of 70 founders of innovative new companies developing disruptive technologies that improve lives Oct. 2022

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At the Myotonic Dystrophy Foundation Annual conference Juvena Therapeutics joins a community of advocates, people who suffer from this most common muscular dystrophy, their families, caregivers, clinical leaders and experts, and Industry leaders developing therapeutics for this major unmet medical need Sept. 2022

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Rohit Jadhav, PHD

Dr. Rohit Jadhav brings more than 12 years of cross disciplinary experience encompassing the fields of oncology, immune aging and auto-immune diseases. He has extensive experience in algorithm development for diagnostic and prognostic biomarker discovery dealing with diverse datasets investigating the Transcriptome, Epigenome and DNA mutations in clinical cohorts.

Dr. Jadhav earned his B.Tech. in Bioinformatics from India, a M.S. in Bioinformatics from Indiana University, Indianapolis, a PhD in Molecular Medicine from UT Health, San Antonio as a CPRIT pre-doctoral fellow, followed by a postdoctoral fellowship in Immunology at Stanford School of Medicine and Mayo Clinic.

Masters & PhD (2009-2016)

Dr. Jadhav worked on identifying epigenetic biomarkers investigating alterations in DNA methylation across different cancer types including breast, ovarian, endometrial, oral and prostate. He was awarded a Cancer Prevention and Research Institute of Texas (CPRIT) Predoctoral Fellowship, which enabled him to be involved in collaborative projects focusing on non-invasive approaches for biomarker discovery. One such project involved use of single-cell RNA sequencing to study circulating tumor cells and another involved studying DNA methylation in cell free DNA, both from peripheral blood. As a lead bioinformatician for these studies, he implemented classification-based prediction methods to enable identification of a panel of biomarkers to be used in determining treatment approaches for prostate cancer patients belonging to different subtypes. These studies have led to 3 approved patents from his mentor Dr. Tim Huang. During this time, Dr. Jadhav was also a lead author on the study that identified DNA methylation biomarkers capable of identifying predisposition to breast cancer after prenatal exposure to the compound bisphenol A and preventive effects of genistein.

Postdoctoral Fellowship (2017-2022)

Dr. Jadhav’s work at Stanford University and Mayo Clinic with Dr. Jorg Goronzy who is a leading expert in immune aging and auto-immunity, focused on epigenetics in the context of chromatin accessibility and specifically alterations in the immune cell types like CD4 and CD8 T cells during aging and autoimmune diseases like rheumatoid arthritis. He was also a lead author studying epigenetic alterations in exhausted T-cells post checkpoint blockade therapies in collaboration with Dr. Rafi Ahmed from Emory University. During this time Dr. Jadhav built pipelines deployed in on-prem clusters and in the cloud for analyzing and visualizing data from RNA-seq, ATAC-seq, TCR-seq, single cell multiome (RNA+ATAC), single cell Cite-seq (RNA+Protein) among others.

Dr. Jadhav has published over 30 peer-reviewed papers with over a thousand citations.

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The Ending Age-Related Diseases Conference Featured Juvena CEO and CO-Founder, Hanadie Yousef, PhD, as a leading aging biology expert discussing “Building a Pipeline of Therapeutics that Target Diseases of Aging” and Dr. Thach Mai, leading Discovery Scientist, discussing Juvena’s innovative ML-enhanced platform for protein drug discovery Aug. 2022

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Munir Yousef, MS

Munir Yousef joined Juvena Therapeutics as a bioinformatics analyst to contribute to Juvena’s growing platform by developing robust data analysis pipelines for their in silico protein drug discovery platform. After realizing his passion for data-driven discovery of solutions to real world problems, Munir obtained his Masters degree in Applied Data Science from Syracuse University.

Before officially joining the team, Munir worked as a data science consultant and helped develop internal data analysis and visualization tools to support Juvena’s growing R&D platforms.

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CSO and Co-Founder Dr. Jeremy O’Connell presents at FASEB Industry Panel Jul. 2022

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Natalie Ploof

Natalie joined Juvena Therapeutics as a Lab Manager to support, implement and optimize laboratory operations to meet the needs of the growing R&D team.

Before joining Juvena, Natalie worked as a Senior Research Associate at GOOD Meat, where she supported cell line development efforts to identify lead cell lines for their cultivated meat projects. Throughout her tenure at GOOD Meat, Natalie focused her efforts on cell bank management, overseeing all operations related to Master and Master Working Cell Banks. This involved creation of large-scale banks, conducting release and stability testing, managing vial inventories, and overseeing transfers to manufacturing partners. In addition to cell bank management, Natalie managed her department’s controlled document system, working to build-out and standardize relevant quality documents. Through her work, Natalie played a key role in the company’s preparation for the recent FDA/USDA clearances for their cultivated chicken product.

Natalie obtained her bachelor’s and master’s degrees in Bioengineering from Santa Clara University. In her free time, she enjoys reading, amateur baking, playing board games with friends, and exploring new neighborhoods in the Bay Area.

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Co-founders, Dr. Hanadie Yousef and Dr. Jeremy O’Connell were invited speakers at the 2nd Annual Longevity Conference in SF. While Yousef gave an oral presentation, O’Connell presented a poster about Juvena’s quantitative proteomics approach for mining the secretome of human pluripotent stem cells.

Jyoti Ahlawat, PHD

Horizon Ventures Techcracker conference spotlights Juvena Co-Founder, Hanadie Yousef, PhD as one of 70 founders of innovative new companies developing disruptive technologies that improve lives Oct. 2022

Rohit Jadhav, PHD

Munir Yousef, MS

CSO and Co-Founder Dr. Jeremy O’Connell presents at FASEB Industry Panel Jul. 2022

Natalie Ploof

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